During a close-quarters fight, target areas on an attacker are the parts of his body that make him dangerous to you. Your goal should be to neutralize the danger by attacking these areas, particularly those that allow him to wield a weapon. Most likely, the target areas will be the shoulder, which allows him to swing or thrust his weapon, the wrist and major muscles in the arm, which allow him to hold onto the weapon, and the muscles in the leg, which help him to stay on his feet. By neutralizing these target areas, you’ll be able to protect yourself and escape the danger.